![]() There was no significant effect on auditory threshold at a range of frequencies. Breathing end-tidal 10% and 20% N2O significantly increased middle ear pressure, and produced a significant effect on the subjective interpretation of a sound's intensity. Observations were made in the breathing mediums of room air in the control stages (Stages 1 and 4), compared to N2O and supplemental oxygen (Stages 2 and 3), in 16 human subjects in a quiet room. ![]() Subjects also qualitatively interpreted three intensity levels using a subjective intensity test. This study examined auditory threshold levels, acoustic impedance, acoustic perception, memory, and discrimination to determine if hearing was altered by end-tidal 10% or 20% nitrous oxide. This increase can be interpreted as hearing low intensity sounds more loudly. There is a belief that the administration of nitrous oxide (N2O) increases hearing acuity. ![]()
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